Tag Archives: Confocal Microscopy

Laser Scanning Microscopes (LSM) by ZEISS: The benchmark in confocal microscopy

Automated microscope for gentle and fast confocal 4D imaging

Enhancing ZEISS Celldiscoverer 7 with ZEISS LSM 900 for optical sectioning

Primary lung fibroblasts imaged with ZEISS Celldiscoverer 7 with LSM 900

By adding ZEISS LSM 900 with Airyscan 2 to ZEISS Celldiscoverer 7, users get the ease-of-use and automation from a fully integrated microscope platform and the superb confocal image quality and flexibility of the ZEISS LSM 9 family with Airyscan 2. The new Multiplex mode allows the user to perform superresolution 3D imaging with up to 1.5x higher resolution. Additionally, researchers can easily separate multiple labels with spectral imaging.


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New Multiplex mode for ZEISS Airyscan 2 enables fast and gentle confocal microscopy

ZEISS LSM 9 family for life sciences research introduced

HeLa cells imaged with ZEISS Airyscan 2
The new Multiplex mode for ZEISS Airyscan 2 delivers more information in less time. Smart illumination and detection schemes allow parallel pixel acquisition for fast and gentle confocal microscopy. Researchers can now image their most challenging three-dimensional samples with high framerates in superresolution.


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Why do dopamine neurons die particularly fast in a specific brain area?

Research team from York uses confocal microscopy from ZEISS to investigate neurodegeneration processes in Parkinson’s disease

Dopamine neurons under the confocal microscope

A key question in Parkinson’s disease is why dopamine neurons die particularly fast in a specific area of the midbrain. In a recent paper, a research team from the University of York studied Drosophila neurons using ZEISS LSM 780 in the Bioscience Technology Facility to investigate basic processes of this neurodegenerative disease. They proposed that variations in the expression of a specific protein contribute to differences in neurodegeneration seen in Parkinson’s disease.


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Foundation stone ceremony for world-class high-resolution microscopy centre in Heidelberg

ZEISS supports new EMBL Imaging Centre with solutions for correlative microscopy

Rendering of the new EMBL Imaging Centre

The new EMBL Imaging Centre, to be opened in 2021 and located on the campus of the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, will give researchers access to the most modern microscopy technologies available. ZEISS supports the centre with solutions for correlative microscopy.


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Spotlight on the cells’ ultrastructure

New correlative approach combines superresolution confocal and scanning electron imaging

The Radboundumc research team

Researchers from the Department of Cell Biology, theme Nanomedicine, and the ‘Microscopy Imaging Center’ at the Radboudumc in Nijmegen, Netherlands recently developed and optimized a pipeline for correlative imaging using superresolution (SR) microscopy and scanning electron microscopy (SEM) to study the cellular ultrastructure.


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The lamprey regenerates its spinal cord not just once – but twice

Marine Biological Laboratory (MBL) scientists determine central nervous system regeneration with ZEISS microscopes

Lamprey spinal cord

The eel-like lamprey can fully regenerate its spinal cord even after it’s been severed. In a new study, Marine Biological Laboratory (MBL) scientists report that lampreys recover and regenerate just as impressively after a second complete spinal cord injury at the same location. A recent study by Marine Biological Laboratory (MBL) scientists opens up a new path for identifying pro-regenerative molecules and potential therapeutic targets for human spinal cord injury.


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What do metallographers actually do?

The microscope as the most important tool

Toni Vegaz Nguyen, who himself trained as a metallographer at the Lette Verein Berlin, explains what a metallographer does, why he needs microscopes for it.

Metallographers mainly deal with the microstructure of materials and contribute to quality assurance. This also includes mechanical-technological and non-destructive material testing, material development, and research of high-quality materials as well as damage analysis.


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“The main goal of my research is to set up screening clinics throughout the developing world”

Johns Hopkins researcher Dr Saraswati Sukumar gives an insight into her work on breast cancer

araswati Sukumar - Johns Hopkins Medicine

Focusing on breast cancer, Dr Saraswati Sukumar’s research aims to improve early detection and therefore save patients the difficulties associated with treatment. In this short interview, the Johns Hopkins Medicine researcher describes the progress of her research, as well as the challenges and opportunities that lie ahead.


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African students fascinated by the possibilities of confocal microscopy

Microscopy and image analysis course at University of Ghana

The participants of the microscopy and image analysis course at University of Ghana showed a great level of enthusiasm.

Recently, the two-week course “Introduction to fluorescent microscopy and image analysis techniques” was held at the West African Centre for Cell Biology of Infectious Pathogens (WACCBIP) at University of Ghana at Legon. It helped 15 Master’s and PhD students from different universities in Ghana and Senegal gain a basic understanding of light microscopy techniques and computerized image analysis.


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A journey into a human kidney

ZEISS microscopes help uncover centuries old hidden secrets of human kidney stones

Kidney stones, the painful urinary deposits that affect more than 10 percent of people worldwide, are surprisingly dynamic, forming much like microscopic coral reefs, according to new research that could provide insights into how to better diagnose and treat the condition.


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