Kidney stones, the painful urinary deposits that affect more than 10 percent of people worldwide, are surprisingly dynamic, forming much like microscopic coral reefs, according to new research that could provide insights into how to better diagnose and treat the condition.
A team of Sydney scientists – including Katharina Gaus from University of New South Wales (UNSW) – have made a groundbreaking discovery in telomere biology with implications for conditions ranging from cancer to ageing and heart disease. The unique area detector technology of ZEISS LSM 880 with Airyscan made it possible to image telomere structures.
At Neuroscience 2017, a new processing mode for the ZEISS LSM 8 family with Airyscan has been introduced. ZEISS Airyscan allows for the unique combination of superresolution imaging with increased sensitivity and acquisition speed. It works with standard samples and dyes, and captures 3D data even in thicker samples that need a higher penetration depth. The unique 32-channel GaAsP array detector captures more spatial information than traditional confocal microscopes. The new 2D Superresolution mode now uses this additional information to create an optical section of 0.2 Airy units (AU) and resolves structures down to 120 nanometer laterally in a single image.
Microscopy is so much more than simply making small things visible. With different microscopy techniques, you can observe living cells in motion, collect three-dimensional measurements, identify chemical elements, count tiny particles, characterize surfaces, create nano structures, and look into the smallest objects without destroying them.
The recently published peer-reviewed paper “Exploring the Potential of Airyscan Microscopy for Live Cell Imaging” by Kseniya Korobchevskaya, B. Christoffer Lagerholm, Huw Colin-York and Marco Fritzsche from the University of Oxford, UK highlights the significant improvement of resolution and signal-to-noise at the same time of ZEISS Airyscan compared to conventional confocal imaging techniques.
Join ZEISS for our largest microscopy tradeshow in North America. Visit us at the 2017 Microscopy & Microanalysis conference to learn about the latest microscopy innovations and advancements through seminars in our booth. Test-drive our newest electron/ion and light microscopes. Challenge our team of experts with your most difficult imaging problems.
On 24 April 2017 ZEISS opened the new ZEISS Microscopy Customer Center Europe at the Oberkochen site. This is the most comprehensive ZEISS Customer Center including light, electron and X-ray microscopy in a single location: here users from Industry and Academia can try out correlative workflows between the different microscopy technologies and also advanced 3D microscopy.
ZEISS Microscopy UK recently kicked off its Life Science Imaging workshops giving microscope users the chance to redefine how they use the latest technology from ZEISS. The day consisted of short but focused talks and hands-on interactive workshops. The sessions provided an overview of the new ZEISS Celldiscoverer 7, Fast Mode for LSM 880 with Airyscan, the recently updated Axio Observer family of inverted research microscopes, and electron microscopy for life sciences with ZEISS Atlas 5. ZEISS experts were on-hand to discuss how the systems can be used to their full potential and demonstrated correlative 3D microscopy solutions from light toelectron/ion and X-ray microscopy.
Laser-scanning confocal microscopy, which enables scientists to construct 3D representations of objects in the range of hundreds of nanometer, has been the workhorse and method of choice for imaging for decades now and has revolutionized our view of biology and life sciences. Scientists at the VIB BioImaging Core, Belgium have taken the potential of confocal microscopy across the diffraction barrier by using innovative software-based image analysis tools. This new, patented methodology now makes this possible through a collaboration between VIB and German microscopy leader ZEISS.
The traditional principle of the LSM beampath forces the user to compromise either on resolution or sensitivity. Resolution is increased by closing the pinhole, at the same time limiting the amount of light that is allowed to pass through to the detector. The Airyscan detector of ZEISS LSM 880 and LSM 800 overcomes this challenge. A new publication list assembles some of the scientific work that has been done with the ZEISS LSM 8 family of confocal microscopy systems. The great variety of applications collectively profits from the light efficient beam path of the LSM systems, and the unique combination of superresolution, high sensitivity and high speed imaging provided by Airyscan.