ZEISS Elyra 7 with Lattice SIM expands the possibilities of structured illumination microscopy (SIM)
ZEISS Elyra 7 with Lattice SIM is a new flexible platform for fast and gentle 3D superresolution. Lattice SIM expands the possibilities of structured illumination microscopy (SIM): illuminating the sample with a lattice pattern rather than grid lines gives higher contrast and allows a more robust image reconstruction. Scientists can use 2x higher sampling efficiency to lower the illumination dosage to observe fast cellular processes in superresolution. High image quality is maintained even at high frame rates.
Fast and gentle superresolution imaging with Lattice SIM
Lattice SIM enables fast imaging of 3D volumes with up to 120 nm laterally. Thanks to greater light efficiency, the new Lattice SIM technology provides scientists with gentle superresolution imaging of living specimens with 255 frames per second. Using less light to illuminate the specimen means scientists can image longer with less bleaching of the sample. The novel Lattice SIM technology allows new mechanistic details to be uncovered and the finest subcellular structures in large fields of view to be quantified.
Understand how Lattice SIM works: