Improved optical sectioning brings higher resolution without acquiring a z-stack
At Neuroscience 2017, a new processing mode for the ZEISS LSM 8 family with Airyscan has been introduced. ZEISS Airyscan allows for the unique combination of superresolution imaging with increased sensitivity and acquisition speed. It works with standard samples and dyes, and captures 3D data even in thicker samples that need a higher penetration depth. The unique 32-channel GaAsP array detector captures more spatial information than traditional confocal microscopes. The new 2D Superresolution mode now uses this additional information to create an optical section of 0.2 Airy units (AU) and resolves structures down to 120 nanometer laterally in a single image.