Knowledge

ZEISS ORION NanoFab contributes to publication in Advanced Biosystems

Helium ions have been used to image viruses attacking bacteria. These bacteriophages viruses represent a possible alternative to antibiotics for treating bacterial infections.

A team from the University of Jyväskylä in Finland has turned to helium ion microscopy. With the help of ZEISS ORION NanoFab they were able to produce high-resolution images of bacteriophages–bacteria interactions at different stages of infection, and also demonstrated the feasibility of using neon and helium milling techniques to reveal subsurface structures.


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ZEISS & Wiley present free guide

This Essential Knowledge Briefing aims to provide a simple introduction to correlative microscopy. It describes the different microscopy techniques that are commonly combined together, outlines the benefits and challenges of these different combinations, and explores how correlative microscopy will develop and advance in the future.


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Comparing Airyscan technology to conventional confocal imaging in live cell imaging

The recently published peer-reviewed paper “Exploring the Potential of Airyscan Microscopy for Live Cell Imaging” by Kseniya Korobchevskaya, B. Christoffer Lagerholm, Huw Colin-York  and Marco Fritzsche from the University of Oxford, UK highlights the significant improvement of resolution and signal-to-noise at the same time of ZEISS Airyscan compared to conventional confocal imaging techniques.


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Interactive techniques for classroom experiments and rehearsals may upgrade your university

Microscopy is an essential part of the life and earth sciences at universities. Students use microscopes to gain deeper insight into preparing and examining human, animal or plant cells. For this, they need various microscopy techniques and software for image acquisition and documentation in their lectures. And this is where the Digital Classroom comes into play: connected ZEISS microscopes, the ZEISS imaging software Labscope and digital equipment such as tablets enable an interactive approach to learning and create a motivating and engaging atmosphere for students. They are also inspired by the possibility of working with the tools they use in their everyday lives at university.


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Phase Contrast Tomography for Quantitative Analysis

Contemporary high performance structural materials like hypereutectic Al-Si alloy is an attractive class of engineering material that finds application in many critical electronic purposes.  Researchers at Naval Materials Research Laboratory (NMRL) in India used a novel approach of friction stir processing (FSP), a variant of severe plastic deformation process, for microstructural refinement.  In an international collaboration between the NMRL and ZEISS Microscopy, non-destructive three dimensional X-ray imaging, performed with ZEISS Xradia 520 Versa was used to investigate the microstructural modifications obtained by FSP on the Al-30Si alloy.


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The Journal of Visualized Experiments (JoVE) is a PubMed-indexed video journal with the mission to increase the productivity of scientific research. Our article features a detailed video protocol for live confocal imaging of developing Arabidopsis flowers with ZEISS stereo and laser scanning microscopy systems. Enjoy the video protocol and let yourself be inspired!


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Imaging of cathode, anode, binder, separator at low accelerating voltages with ZEISS FE-SEM instruments

Rechargeable Li-ion batteries are the power source of choice for portable electronic devices such as cellphones, laptops, cameras, etc. and are becoming increasingly important in the automotive industry and for stationary storage applications. They are complex electrochemical energy storage devices incorporating many material types, ranging from high-density metals to low-density polymers, and require a flexible suite of instrumentation for proper characterization & analysis. Especially challenging are charging effects and the danger of damage on some sensitive components when using higher accelerating voltages in the electron microscope. In this application note, very low voltage imaging was used to investigate the usability of a scanning electron microscope (SEM) on battery materials. The surface and binder of cathode and anode as well as the separator were analyzed.


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A new reference list details scientific work with ZEISS LSM 8 family of confocal microscopes with Airyscan detector

The traditional principle of the LSM beampath forces the user to compromise either on resolution or sensitivity. Resolution is increased by closing the pinhole, at the same time limiting the amount of light that is allowed to pass through to the detector. The Airyscan detector of ZEISS LSM 880 and LSM 800 overcomes this challenge. A new publication list assembles some of the scientific work that has been done with the ZEISS LSM 8 family of confocal microscopy systems. The great variety of applications collectively profits from the light efficient beam path of the LSM systems, and the unique combination of superresolution, high sensitivity and high speed imaging provided by Airyscan.


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ZEISS & Wiley present an exclusive interactive White Paper collection that discusses the challenges of automated microscopy

Often in life sciences research, the data you are after will only be revealed through multiple runs of experiments or complex assays. Automation and parallelization of your imaging can be the only way to get there. Observing live samples over a number of days or imaging lots of multiwell plates really puts your microscope through its paces. To get reproducible, unbiased data, you must control environmental conditions such as light, temperature and CO2. Especially for demanding long-term timelapse fluorescence imaging, you need gentle illumination and a stable platform. This collection of White Papers aims to give you insights into the challenges and recent developments in the ever-expanding world of automated microscopy solutions. Automation can simplify your laboratory setup and make your work more efficient and comfortable.


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