World Cancer Day

Cancer research - ZEISS microscopes provide insights into how cancer proliferates

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‘We can. I can.’ The World Cancer Day on February 4th, 2018 shows how you can do your part to reduce the global burden of cancer and to reduce the impact that cancer has on individuals, families and communities.

Contributing to technological progress for more than 170 years

In cancer research, scientists often use ZEISS microscopes to understand how healthy cells are different to cancer cells. Live cell imaging helps to monitor the dynamic processes in the cell cycle and is often used in cell or animal models. Autofluorescence or fluorescent labels help to distinguish tumor cells and tissue from healthy cells. Such basic research is the very foundation for the development of novel diagnoses, treatments, and cures.

At the German Research Center (DKFZ) in Heidelberg scientists conduct research in over 70 departments, research groups and clinical cooperative units. A large number of traditional widefield and confocal laser scanning microscopes and imaging systems for slide-scanning and high-throughput live cell microscopy from ZEISS support the scientists in addressing their scientific issues.
Associate Prof. Jun Zhan, of Prof. Hongquan Zhang’s team at Peking University Health Science Center, studies the molecular mechanisms of cancer metastasis. She uses ZEISS laser scanning microscopes to observe cancer cells in animal models and patient samples to understand the influence of interacting proteins at cellular level on cancer progression.

Nobel Prizes for the most groundbreaking research

Sir Paul M. Nurse, Leland H. Hartwell and Timothy Hunt were awarded the Nobel Prize for Physiology or Medicine in 2001. Their fundamental discoveries regarding the control of the cell cycle have a great impact on all aspects of cell growth. Defects in cell cycle control may lead to the type of chromosome alterations seen in cancer cells. In the long term, this can open new possibilities for cancer treatment. Harald zur Hausen received the Nobel Prize for Physiology or Medicine in 2008. He revealed that a virus infection can cause cervical cancer – contrary to prevailing doctrines. His discovery was a starting point to successful construction of biosynthetic preventive vaccines against this carcinoma.

Stained microglia cells (responsible for Glioblastoma brain tumors) treated with an experimental drug that stops cell division of tumor cells. Imaged with ZEISS Axio Observer.Z1 , Plan Apo 63x Staining: Nucleus (blue), Actin (red), Microtubules (green)

Learn more about paving new ways for cancer research in the field of microscopy, fluorescence guided tumor resection in neurosurgery and nobel prize winners

Tags: Confocal Microscopy, Electron and Ion Microscopy, Light Microscopy

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